{"id":35440,"date":"2025-03-20T12:14:38","date_gmt":"2025-03-20T05:14:38","guid":{"rendered":"https:\/\/1dddev.com\/chemsci\/?post_type=ku-personnel&#038;p=35440"},"modified":"2025-04-28T16:14:16","modified_gmt":"2025-04-28T09:14:16","slug":"patchreenart-saparpakorn","status":"publish","type":"ku-personnel","link":"https:\/\/1dddev.com\/chemsci\/ku-personnel\/patchreenart-saparpakorn\/","title":{"rendered":"\u0e23\u0e28.\u0e14\u0e23. \u0e1e\u0e31\u0e0a\u0e23\u0e35\u0e19\u0e32\u0e23\u0e16 \u0e17\u0e23\u0e31\u0e1e\u0e22\u0e4c\u0e2d\u0e32\u0e20\u0e32\u0e01\u0e23"},"content":{"rendered":"\n<h2 class=\"wp-block-heading\">\u0e42\u0e0b\u0e40\u0e0a\u0e35\u0e22\u0e25\u0e21\u0e35\u0e40\u0e14\u0e35\u0e22\/\u0e40\u0e27\u0e47\u0e1a\u0e44\u0e0b\u0e15\u0e4c<\/h2>\n\n\n\n<div class=\"grid grid-cols-1 !mb-16 gap-x-4 gap-y-3 | lg:grid-cols-2 lg:gap-x-7\">\n\t\t\t\t\t<a href=\"https:\/\/scholar.google.co.th\/citations?user=PnyM24YAAAAJ&#038;hl=en\" aria-label=\"Google Scholar\" target=\"_blank\" class=\"link__card btn-link rounded-xl flex flex-col justify-between overflow-hidden w-full group border-2 border-black\/30 hover:border-primary\">\n\t\t\t\t\n\t\t\t\t\t<div class=\"grid grid-cols-[1fr_18px] gap-0.5 | xl:gap-3 xl:flex justify-between items-end  relative z-10\">\n\t\t\t\t\t\t<span class=\"text-black text-fs14 | lg:text-fs16\">\n\t\t\t\t\t\t\tGoogle Scholar\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"icon external\">\n\t\t\t\t\t\t\t\t\t<svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" viewBox=\"0 0 14 14\" fill=\"none\">\n\t\t\t\t\t\t\t\t\t\t<path fill=\"black\" d=\"M14 1.49998C14 0.947692 13.5523 0.499987 13 0.5L3.99998 0.500212C3.44769 0.500225 2.99999 0.947951 3 1.50024C3.00001 2.05252 3.44774 2.50023 4.00002 2.50021L12 2.50002L12.0002 10.5C12.0002 11.0523 12.448 11.5 13.0002 11.5C13.5525 11.5 14.0002 11.0523 14.0002 10.5L14 1.49998ZM2.39368 13.5211L13.7071 2.20709L12.2929 0.79291L0.979434 12.1069L2.39368 13.5211Z\" \/>\n\t\t\t\t\t\t\t\t\t<\/svg>\n\t\t\t\t\t\t\t\t\t<svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" viewBox=\"0 0 14 14\" fill=\"none\">\n\t\t\t\t\t\t\t\t\t\t<path fill=\"black\" d=\"M14 1.49998C14 0.947692 13.5523 0.499987 13 0.5L3.99998 0.500212C3.44769 0.500225 2.99999 0.947951 3 1.50024C3.00001 2.05252 3.44774 2.50023 4.00002 2.50021L12 2.50002L12.0002 10.5C12.0002 11.0523 12.448 11.5 13.0002 11.5C13.5525 11.5 14.0002 11.0523 14.0002 10.5L14 1.49998ZM2.39368 13.5211L13.7071 2.20709L12.2929 0.79291L0.979434 12.1069L2.39368 13.5211Z\" \/>\n\t\t\t\t\t\t\t\t\t<\/svg>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\n\n<\/div>\n\n\n<h2 class=\"wp-block-heading\">\u0e27\u0e38\u0e12\u0e34\u0e01\u0e32\u0e23\u0e28\u0e36\u0e01\u0e29\u0e32<\/h2>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Ph.D. (Chemistry), Kasetsart University<\/li>\n\n\n\n<li>B.Sc. (Chemistry, 2nd Class Honours), Kasetsart University<\/li>\n<\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">\u0e07\u0e32\u0e19\u0e27\u0e34\u0e08\u0e31\u0e22<\/h2>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Computer-aided drug design (ex. Virtual Screening, Molecular Docking, Quantitative Structure Activity Relationship (QSAR)), HIV-1 RT&nbsp;<\/li>\n\n\n\n<li>To better understand the key interaction of drugs or molecules in the biological targets and predict the photophysical properties which will be helpful for designing the new potent compounds<\/li>\n\n\n\n<li>Using Molecular docking and quantum chemical calculations\n<ol class=\"wp-block-list\">\n<li> Divide-and-conquer based quantum chemical study\n<ul class=\"wp-block-list\">\n<li>Interaction between HIV-1 RT and NNRTIs<\/li>\n\n\n\n<li> Mechanism of the West Nile Virus NS3 Protease Inhibitor<\/li>\n\n\n\n<li>Other targets; ex. Dengue virus, Alzheimer disease etc.<\/li>\n<\/ul>\n<\/li>\n\n\n\n<li>Binding and photophysical investigation of DNA intercalating dye\n<ul class=\"wp-block-list\">\n<li>Adsorption and emission properties of fluorescence dyes; ex. picogreen, used in the biological assay<\/li>\n<\/ul>\n<\/li>\n\n\n\n<li>Determination of the absolute configuration using electronic circular dichroism spectra\n<ul class=\"wp-block-list\">\n<li>Assign the absolute configuration of the natural compounds<\/li>\n<\/ul>\n<\/li>\n<\/ol>\n<\/li>\n<\/ul>\n\n\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"580\" height=\"201\" src=\"http:\/\/1dddev.com\/chemsci\/wp-content\/uploads\/2025\/03\/pnsk1.png\" alt=\"\" class=\"wp-image-35414\" srcset=\"https:\/\/1dddev.com\/chemsci\/wp-content\/uploads\/2025\/03\/pnsk1.png 580w, https:\/\/1dddev.com\/chemsci\/wp-content\/uploads\/2025\/03\/pnsk1-300x104.png 300w\" sizes=\"auto, (max-width: 580px) 100vw, 580px\" \/><\/figure>\n\n\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"580\" height=\"201\" src=\"http:\/\/1dddev.com\/chemsci\/wp-content\/uploads\/2025\/03\/pnsk2.png\" alt=\"\" class=\"wp-image-35415\" srcset=\"https:\/\/1dddev.com\/chemsci\/wp-content\/uploads\/2025\/03\/pnsk2.png 580w, https:\/\/1dddev.com\/chemsci\/wp-content\/uploads\/2025\/03\/pnsk2-300x104.png 300w\" sizes=\"auto, (max-width: 580px) 100vw, 580px\" \/><\/figure>\n\n\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"580\" height=\"227\" src=\"http:\/\/1dddev.com\/chemsci\/wp-content\/uploads\/2025\/03\/pnsk3.png\" alt=\"\" class=\"wp-image-35416\" srcset=\"https:\/\/1dddev.com\/chemsci\/wp-content\/uploads\/2025\/03\/pnsk3.png 580w, https:\/\/1dddev.com\/chemsci\/wp-content\/uploads\/2025\/03\/pnsk3-300x117.png 300w\" sizes=\"auto, (max-width: 580px) 100vw, 580px\" \/><\/figure>\n\n\n\n<h2 class=\"wp-block-heading\">\u0e1c\u0e25\u0e07\u0e32\u0e19\u0e27\u0e34\u0e08\u0e31\u0e22<\/h2>\n\n\n\n<ol class=\"wp-block-list\">\n<li>Saparpakorn P, Hannongbua S, Rognan D. Design of nevirapine derivatives insensitive to the K103N and Y181C HIV-1) reverse transcriptase mutants. SAR QSAR Environ Res., 2006, 17, 183-94.<\/li>\n\n\n\n<li>Pungpo P, Saparpakorn P, Wolschann P, Hannongbua S. Computer-aided molecular design of highly potent HIV-1 RT inhibitors: 3D QSAR and molecular docking studies of efavirenz derivatives. SAR QSAR Environ Res. 2006, 17, 353-70.<\/li>\n\n\n\n<li>Khunnawutmanotham N, Chimnoi N, Saparpakorn P, Pungpo P, Louisirirotchanakul S, Hannongbua S, Techasakul S. Novel 2-chloro-8-arylthiomethyldipyridodiazepi-none derivatives with activity against HIV-1 reverse transcriptase. Molecules 2007, 12, 218-230.<\/li>\n\n\n\n<li>Saparpakorn P, Kim J, Hannongbua S. Investigation on the binding of polycyclic aromatic hydrocarbons with soil organic matter; A theoretical approach., Molecules 2007, 12, 703-715.<\/li>\n\n\n\n<li>Pungpo P, Punkvang A, Saparpakorn P, Hannongbua S. Chapter VIII &#8211; Understanding the Interaction and the Structure-Activity Correlation of HIV-1 RT Inhibitors of Efavirenz Derivatives and WT and K103N HIV-1 RT using Molecular Docking, 3D-QSAR Approaches and Quantum Chemical Calculations, Drug Design Research Perspectives , 2007, 213-249.<\/li>\n\n\n\n<li>Pungpo P, Punkvang A, Saparpakorn P, Hannongbua S. Understanding the interaction and the structure-activity correlation of efavirenz derivatives and WT and K103N HIV-1 RT by molecular docking and 3D-QSAR approaches, Infect. Gen. Evol., 2008, 8, S43.<\/li>\n\n\n\n<li>Ming Ge H., Yun Zhang W., Ding G., Saparpakorn P., Chun Song Y., Hannongbua S., Xiang Tan R. Chaetoglobins A and B, two unusual alkaloids from endophytic Chaetomium globosum culture, Chem. Comm. 2008, 45, 5978-5980<\/li>\n\n\n\n<li>Saparpakorn, P., M. Kobayashi, H. Nakai. 2013. \u201cDivide-and-Conquer Electronic-Structure Study on the Mechanism of the West Nile Virus NS3 Protease Inhibitor\u201d <em>Bull. Chem. Soc. Jpn.<\/em>86: 67-74.<\/li>\n\n\n\n<li>Saparpakorn, P., M. Kobayashi, S. Hannongbua, H. Nakai. 2013. \u201cDivide-and-Conquer Based Quantum Chemical Study for Interaction between HIV-1 Reverse Transcriptase and MK-4965 Inhibitor\u201d <em>Int. J. Quant. Chem.<\/em> 113: 510-517.<\/li>\n\n\n\n<li>Okoshi M., P. Saparpakorn, Y. Takada, S. Hannongbua, H. Nakai. 2014. \u201cTheoretical Study on the Selective Fluorescence of PicoGreen: Binding Models and Photophysical Properties\u201d <em>Bull. Chem. Soc. Jpn. <\/em>87: 267-273.<\/li>\n\n\n\n<li>Kamsri, P., A. Punkvang, S. Hannongbua, P. Saparpakorn, P. Pungpo. 2015. \u201cElucidating Structural Basis of Benzofuranpyrrolidinepyrazole Derivatives for Enhancing Potency against Both the InhA Enzyme and Intact M. Tuberculosis Cells: ACombined MD Simulations and 3D-QSAR Study\u201d <em>RSC Adv.<\/em> 5: 52926-52937.<\/li>\n<\/ol>\n","protected":false},"featured_media":35413,"parent":0,"template":"","meta":{"_acf_changed":false,"footnotes":""},"class_list":["post-35440","ku-personnel","type-ku-personnel","status-publish","has-post-thumbnail","hentry"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v26.3 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>\u0e23\u0e28.\u0e14\u0e23. \u0e1e\u0e31\u0e0a\u0e23\u0e35\u0e19\u0e32\u0e23\u0e16 \u0e17\u0e23\u0e31\u0e1e\u0e22\u0e4c\u0e2d\u0e32\u0e20\u0e32\u0e01\u0e23 - \u0e20\u0e32\u0e04\u0e27\u0e34\u0e0a\u0e32\u0e40\u0e04\u0e21\u0e35 \u0e04\u0e13\u0e30\u0e27\u0e34\u0e17\u0e22\u0e32\u0e28\u0e32\u0e2a\u0e15\u0e23\u0e4c \u0e21\u0e2b\u0e32\u0e27\u0e34\u0e17\u0e22\u0e32\u0e25\u0e31\u0e22\u0e40\u0e01\u0e29\u0e15\u0e23\u0e28\u0e32\u0e2a\u0e15\u0e23\u0e4c<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/1dddev.com\/chemsci\/ku-personnel\/patchreenart-saparpakorn\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"\u0e23\u0e28.\u0e14\u0e23. \u0e1e\u0e31\u0e0a\u0e23\u0e35\u0e19\u0e32\u0e23\u0e16 \u0e17\u0e23\u0e31\u0e1e\u0e22\u0e4c\u0e2d\u0e32\u0e20\u0e32\u0e01\u0e23 - 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