{"id":35065,"date":"2025-06-12T15:47:14","date_gmt":"2025-06-12T08:47:14","guid":{"rendered":"https:\/\/1dddev.com\/biochemistrysci\/?post_type=ku-personnel&#038;p=35065"},"modified":"2025-06-12T15:47:15","modified_gmt":"2025-06-12T08:47:15","slug":"%e0%b8%a3%e0%b8%ad%e0%b8%87%e0%b8%a8%e0%b8%b2%e0%b8%aa%e0%b8%95%e0%b8%a3%e0%b8%b2%e0%b8%88%e0%b8%b2%e0%b8%a3%e0%b8%a2%e0%b9%8c-%e0%b8%94%e0%b8%a3-%e0%b8%a0%e0%b8%b2%e0%b8%99%e0%b8%b8-%e0%b8%9e","status":"publish","type":"ku-personnel","link":"https:\/\/1dddev.com\/biochemistrysci\/ku-personnel\/%e0%b8%a3%e0%b8%ad%e0%b8%87%e0%b8%a8%e0%b8%b2%e0%b8%aa%e0%b8%95%e0%b8%a3%e0%b8%b2%e0%b8%88%e0%b8%b2%e0%b8%a3%e0%b8%a2%e0%b9%8c-%e0%b8%94%e0%b8%a3-%e0%b8%a0%e0%b8%b2%e0%b8%99%e0%b8%b8-%e0%b8%9e\/","title":{"rendered":"\u0e23\u0e2d\u0e07\u0e28\u0e32\u0e2a\u0e15\u0e23\u0e32\u0e08\u0e32\u0e23\u0e22\u0e4c \u0e14\u0e23.\u0e20\u0e32\u0e19\u0e38 \u0e1e\u0e34\u0e21\u0e1e\u0e4c\u0e27\u0e34\u0e23\u0e34\u0e22\u0e30\u0e01\u0e38\u0e25"},"content":{"rendered":"\n<p><strong>Education Background<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>2017 Ph.D. (Biochemistry), Mahidol University<\/li>\n\n\n\n<li>2011 B.Sc. (Chemistry, First class honour), Mahidol University<\/li>\n<\/ul>\n\n\n\n<p><strong>Area of Expertise<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Protein expression and purification<\/li>\n\n\n\n<li>Enzyme kinetic mechanism<\/li>\n\n\n\n<li>Enzyme structure and function<\/li>\n\n\n\n<li>Enzyme engineering<\/li>\n<\/ul>\n\n\n\n<p><strong>Research Interests<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Study of pre-steady state kinetic and protein structure of flavin-dependent enzymes.<\/li>\n\n\n\n<li>Development of enzyme efficiency and stability as powerful biocatalyst by enzyme engineering.<\/li>\n<\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Research focus<\/h2>\n\n\n\n<figure class=\"wp-block-image size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"723\" height=\"1024\" src=\"https:\/\/1dddev.com\/biochemistrysci\/wp-content\/uploads\/2025\/06\/image-24-723x1024.png\" alt=\"\" class=\"wp-image-35067\" srcset=\"https:\/\/1dddev.com\/biochemistrysci\/wp-content\/uploads\/2025\/06\/image-24-723x1024.png 723w, https:\/\/1dddev.com\/biochemistrysci\/wp-content\/uploads\/2025\/06\/image-24-212x300.png 212w, https:\/\/1dddev.com\/biochemistrysci\/wp-content\/uploads\/2025\/06\/image-24-768x1088.png 768w, https:\/\/1dddev.com\/biochemistrysci\/wp-content\/uploads\/2025\/06\/image-24.png 793w\" sizes=\"auto, (max-width: 723px) 100vw, 723px\" \/><\/figure>\n\n\n\n<p><strong>Examples of publications<\/strong><\/p>\n\n\n\n<div class=\"grid grid-cols-1 !mb-16 gap-x-4 gap-y-3 | lg:grid-cols-2 lg:gap-x-7\">\n\t\t\t\t\t<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=Pimviriyakul+P&#038;sort=date&#038;size=200\" aria-label=\"Pubmed\" target=\"_blank\" class=\"link__card btn-link rounded-xl flex flex-col justify-between overflow-hidden w-full group border-2 border-black\/30 hover:border-primary\">\n\t\t\t\t\n\t\t\t\t\t<div class=\"grid grid-cols-[1fr_18px] gap-0.5 | xl:gap-3 xl:flex justify-between items-end  relative z-10\">\n\t\t\t\t\t\t<span class=\"text-black text-fs14 | lg:text-fs16\">\n\t\t\t\t\t\t\tPubmed\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"icon external\">\n\t\t\t\t\t\t\t\t\t<svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" viewBox=\"0 0 14 14\" fill=\"none\">\n\t\t\t\t\t\t\t\t\t\t<path fill=\"black\" d=\"M14 1.49998C14 0.947692 13.5523 0.499987 13 0.5L3.99998 0.500212C3.44769 0.500225 2.99999 0.947951 3 1.50024C3.00001 2.05252 3.44774 2.50023 4.00002 2.50021L12 2.50002L12.0002 10.5C12.0002 11.0523 12.448 11.5 13.0002 11.5C13.5525 11.5 14.0002 11.0523 14.0002 10.5L14 1.49998ZM2.39368 13.5211L13.7071 2.20709L12.2929 0.79291L0.979434 12.1069L2.39368 13.5211Z\" \/>\n\t\t\t\t\t\t\t\t\t<\/svg>\n\t\t\t\t\t\t\t\t\t<svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" viewBox=\"0 0 14 14\" fill=\"none\">\n\t\t\t\t\t\t\t\t\t\t<path fill=\"black\" d=\"M14 1.49998C14 0.947692 13.5523 0.499987 13 0.5L3.99998 0.500212C3.44769 0.500225 2.99999 0.947951 3 1.50024C3.00001 2.05252 3.44774 2.50023 4.00002 2.50021L12 2.50002L12.0002 10.5C12.0002 11.0523 12.448 11.5 13.0002 11.5C13.5525 11.5 14.0002 11.0523 14.0002 10.5L14 1.49998ZM2.39368 13.5211L13.7071 2.20709L12.2929 0.79291L0.979434 12.1069L2.39368 13.5211Z\" \/>\n\t\t\t\t\t\t\t\t\t<\/svg>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\n\t\t\t\t<a href=\"https:\/\/www.scopus.com\/authid\/detail.uri?authorId=57193747752\" aria-label=\"Scopus\" target=\"_blank\" class=\"link__card btn-link rounded-xl flex flex-col justify-between overflow-hidden w-full group border-2 border-black\/30 hover:border-primary\">\n\t\t\t\t\n\t\t\t\t\t<div class=\"grid grid-cols-[1fr_18px] gap-0.5 | xl:gap-3 xl:flex justify-between items-end  relative z-10\">\n\t\t\t\t\t\t<span class=\"text-black text-fs14 | lg:text-fs16\">\n\t\t\t\t\t\t\tScopus\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"icon external\">\n\t\t\t\t\t\t\t\t\t<svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" viewBox=\"0 0 14 14\" fill=\"none\">\n\t\t\t\t\t\t\t\t\t\t<path fill=\"black\" d=\"M14 1.49998C14 0.947692 13.5523 0.499987 13 0.5L3.99998 0.500212C3.44769 0.500225 2.99999 0.947951 3 1.50024C3.00001 2.05252 3.44774 2.50023 4.00002 2.50021L12 2.50002L12.0002 10.5C12.0002 11.0523 12.448 11.5 13.0002 11.5C13.5525 11.5 14.0002 11.0523 14.0002 10.5L14 1.49998ZM2.39368 13.5211L13.7071 2.20709L12.2929 0.79291L0.979434 12.1069L2.39368 13.5211Z\" \/>\n\t\t\t\t\t\t\t\t\t<\/svg>\n\t\t\t\t\t\t\t\t\t<svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" viewBox=\"0 0 14 14\" fill=\"none\">\n\t\t\t\t\t\t\t\t\t\t<path fill=\"black\" d=\"M14 1.49998C14 0.947692 13.5523 0.499987 13 0.5L3.99998 0.500212C3.44769 0.500225 2.99999 0.947951 3 1.50024C3.00001 2.05252 3.44774 2.50023 4.00002 2.50021L12 2.50002L12.0002 10.5C12.0002 11.0523 12.448 11.5 13.0002 11.5C13.5525 11.5 14.0002 11.0523 14.0002 10.5L14 1.49998ZM2.39368 13.5211L13.7071 2.20709L12.2929 0.79291L0.979434 12.1069L2.39368 13.5211Z\" \/>\n\t\t\t\t\t\t\t\t\t<\/svg>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\n\n<\/div>\n\n\n<ul class=\"wp-block-list\">\n<li>Pimviriyakul, P.<em>, Chaiyen, P. (2022) Formation and Stabilization of C4a-hydroperoxy-FAD by the Arg\/Asn pair in HadA Monooxygenase. FEBS Journal, article in press. Pimviriyakul, P.<\/em>, Pholert, P., Somjitt, S., Choowongkomon, K. (2022) Role of Conserved Arginine in HadA Monooxygenase for 4-Nitrophenol and 4-Chlorophenol Detoxification. Proteins: Structure, Function, and Bioinformatics, 90(6), 1291-1302.<\/li>\n\n\n\n<li>Muenwongtham, S., Jaturapiree, P., Pimviriyakul, P.* (2022) Effect of supplemented sugar in LB medium on the growth of Escherichia coli BL21(DE3) and recombinant protein production. Agriculture and Natural Resources, 56(3), 537-546.<\/li>\n\n\n\n<li>Trisivirat, D., Sutthaphirom, C., Pimviriyakul, P., Chaiyen, P. (2022) Dual activities of oxidation and oxidative decarboxylation by flavoenzymes. ChemBioChem, 23(11), e202100666.<\/li>\n\n\n\n<li>Pimviriyakul, P., Jaruwat, A., Chitnumsub, P., Chaiyen, P. (2021) Structural insights into a flavin-dependent dehalogenase HadA explain catalysis and substrate inhibition via quadruple p-stacking. Journal of Biological Chemistry, 297(2), 100952.<\/li>\n\n\n\n<li>Tinikul, R., Lawan, N., Akeratchatapan, N., Pimviriyakul, P., Chinantuya, W., Suadee, C., Sucharitakul, J., Chenprakhon, P., Ballou, D.P., Entsch, B., Chaiyen, P. (2021) Protonation status and control mechanism of flavin-oxygen intermediates in the reaction of bacterial luciferase. FEBS Journal, 288(10), 3246-3260.<\/li>\n\n\n\n<li>Pimviriyakul, P., Wongnate, T., Tinikul, R., Chaiyen, P. (2020) Minireview: Microbial degradation of halogenated aromatics: molecular mechanisms and enzymatic reactions. Microbial Biotechnology, 13(1), 67 \u2013 86.<\/li>\n\n\n\n<li>Pongpamorn, P., Watthaisong, P., Pimviriyakul, P., Jaruwat, A., Lawan, N., Chitnumsub, P., Chaiyen, P. (2019) Identification of a hotspot residue for improving the thermostability of a flavin-dependent monooxygenase. ChemBioChem, 20(24), 3020 \u2013 3031.<\/li>\n\n\n\n<li>Watthaisong, P., Pongpamorn, P., Pimviriyakul, P., Maenpuen, S, Ohmiya, Y., Chaiyen, P. (2019) A chemo-enzymatic cascade for smart detection of nitro- and halogenated phenols. Angewandte Chemie International Edition, 58, 13254 \u201313258.<\/li>\n\n\n\n<li>Pimviriyakul, P., Chaiyen, P. (2018) A complete bioconversion cascade for dehalogenation and denitration by bacterial flavin\u2013dependent enzymes. Journal of Biological Chemistry, 293(48), 18525-18539.<\/li>\n\n\n\n<li>Pimviriyakul, P., Surawattanawong, P., Chaiyen, P. (2018) Oxidative dehalogenation and denitration by a flavin-dependent monooxygenase is controlled by substrate deprotonation. Chemical Science, 9, 7468-7482.<\/li>\n\n\n\n<li>Pimviriyakul, P., Thotsaporn, K., Sucharitakul, J., Chaiyen, P. (2017) Kinetic mechanism of the dechlorinating flavin-dependent monooxygenase HadA. Journal of Biological Chemistry, 292(12), 4818-4832.<\/li>\n<\/ul>\n\n\n\n<p><strong>Chapter in book<\/strong><\/p>\n\n\n\n<ol class=\"wp-block-list\">\n<li>Pimviriyakul, P., Chaiyen, P. (2020) Overview of flavin-dependent enzymes in The Enzymes, Academic Press. 47, in press.<\/li>\n\n\n\n<li>Chenprakhon, P., Pimviriyakul, , Tongsook, C, Chaiyen, P. (2020) Phenolic hydroxylases in The Enzymes, Academic Press. 47, in press.<\/li>\n\n\n\n<li>Pimviriyakul, P., Chaiyen, P. (2020) Flavin-dependent dehalogenases in The Enzymes, Academic Press. 47, in press.<\/li>\n<\/ol>\n\n\n\n<p><\/p>\n","protected":false},"featured_media":35066,"parent":0,"template":"","meta":{"_acf_changed":false,"footnotes":""},"class_list":["post-35065","ku-personnel","type-ku-personnel","status-publish","has-post-thumbnail","hentry"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v25.2 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>\u0e23\u0e2d\u0e07\u0e28\u0e32\u0e2a\u0e15\u0e23\u0e32\u0e08\u0e32\u0e23\u0e22\u0e4c \u0e14\u0e23.\u0e20\u0e32\u0e19\u0e38 \u0e1e\u0e34\u0e21\u0e1e\u0e4c\u0e27\u0e34\u0e23\u0e34\u0e22\u0e30\u0e01\u0e38\u0e25 - \u0e20\u0e32\u0e04\u0e27\u0e34\u0e0a\u0e32\u0e0a\u0e35\u0e27\u0e40\u0e04\u0e21\u0e35 SCI KU<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" 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